Sentence examples for support for the rationale from inspiring English sources
More importantly, our study provides support for the rationale of combining CUDC-101 with modulators of ABC drug transporters to improve drug efficacy and overcome multidrug resistance associated with the overexpression of ABCB1 and ABCG2.
These results provide further support for the rationale to use "direct" host T cell therapy for prolongation of allograft viability as an alternative to "indirect" therapy mediated by donor T cell infusion.
These data also provide support for the rationale of targeting c-IAP proteins to promote cell death through the activation of an autocrine TNF-dependent pathway.
The finding that tifacogin has bacterial clearance activity in addition to its anticoagulant activity is additional support for the rationale underlying Chiron's ongoing phase III study of tifacogin in patients with severe community-acquired pneumonia.
In conclusion, these results, in the context of other recently reported retrospective studies and adjuvant trials, provide support for the rationale of using adjuvant trastuzumab in this subgroup of patients, who are typically classified as having very good prognosis.
Utilising a hypoxia-activated prodrug such as TH-302 is an exciting approach, and the four on-going clinical trials combining this with anti-angiogenic therapies may provide strong support for the rationale.
Moreover, since publication of the 2012 study [ 26], the peer-reviewed medical literature has provided further basic science and clinical support for the scientific rationale [ 6, 7, 17, 21, 26, 31– 37, 47, 59, 63, 65– 67, 69, 71, 75, 83– 120].
The garbled transcript offers some support for that rationale.
Restoration guidelines generally recommend the use of local seed for ecological and genetic reasons, but there is not always empirical support for the principle-based rationale.
Our findings therefore add support to the rationale for ongoing clinical trials in which higher doses of rifampin for treatment of tuberculosis are being evaluated.
This evidence for synergy supports the rationale for investigating multimodal therapies involving immunotherapy and other anticancer agents with potentially immunosupportive mechanisms of action.
