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A comprehensive environment providing adequate computer support for the evolution of complex ontologies is envisioned.
Current approaches to DSS design are constrained in terms of their ability to adapt to changes in user requirements and to provide support for the evolution of systems.
Support for the evolution of modularity by selection derives predominantly from theoretical studies (see review in Wagner et al. 2007; also see Hansen 2006).
These studies have provided convincing support for the evolution and maintenance of polyandry based on the good genes [ 31, 32], and compatible genes hypotheses [ 35].
Crucially, a recent quantitative genetic analysis of male and female reproductive traits confirmed that sperm length is genetically correlated (negatively) with spermathecal size [ 64], providing explicit support for the evolution of sperm phenotypes via cryptic female choice.
This has meant in turn that there is a greater emphasis in CancerGrid upon support for the evolution of descriptions and protocols - with software artifacts (such as forms and queries) being generated to match successive versions of a model.
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The lack of an adequate support for monitoring the evolution of physical variables prevents the suitable exploitation of the information obtained when monitoring critical patients.
The problem is the lack of support for this evolution.
The alternative methods of phylogenetic tree construction, minimum evolution and maximum likelihood, were tested, but the support for the minimum evolution tree was not sufficient (data not shown).
However, the reward to the reader from the pages-long description of how these "flap polymorphisms" support models for the evolution of clan AA may not justify the burden.
We would like to acknowledge funding support for the Teaching Evolution through Human Examples project from National Science Foundation DRK-12 Grant DRL-1119468.
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