Sentence examples for support anchorage from inspiring English sources

The first study which systematically evaluated the expression and function of different OPN splice forms in breast cancer indicated that OPN-C was selectively expressed in invasive breast cancer and more likely to support anchorage independent tumor growth than OPN-A in a breast cancer cell line.

While one study suggested that OPN-C was selectively expressed in invasive breast cancer and more likely to support anchorage independent tumor growth than OPN-A [24], another study indicated that OPN-C was less likely to promote cell migration and invasion than the other 2 OPN isoforms in mesothelioma cells [25].

In contrast to what we observed previously for SOCS5, co-depletion of SOCS5/6 proved to be sufficient to support anchorage independent growth and colony formation in soft agar (Fig 1B).

Reciprocally, activation of endogenous YAP and TAZ by depletion of LATS2 was sufficient to bypass the requirement for RasV12 to support anchorage independent growth in vitro and to support tumor formation in mouse xenograft assays (Fig 2C, Table 1, Supplementary Figs S3 and S5).

We observed that membrane targeting of CK1ε is required for it to support anchorage-independent growth and that the APC-mutated line DU4475 is relatively resistant to CSNK1E suppression, implicating a role for CSNK1E upstream of APC.

The objectives of this study were to investigate the suitability of the skeletonized distal jet for translatory molar distalization and to check the quality of the supporting anchorage setup.

We determined that ERK but not PI3K or RalGEF activation of HMEC16C cells supports anchorage independent proliferation independent of EGFR activation.

Henry was also responsible for the creation of a permanent navy, with the supporting anchorages and dockyards.

Thus, TG2 expression supported anchorage-independent growth of mammary epithelial cells in soft-agar, disrupted the apical-basal polarity, and resulted in disorganized acini structures when grown in 3D-culture.

Consistent with the pro-anoikis activity of ROS, treatment with a variety of antioxidants suppresses anoikis, supports anchorage-independent cell growth/survival in soft agar, and delays luminal clearance during acinar morphogenesis in vitro.

These results suggest that autocrine TGFβ appears to support both anchorage-dependent and anchorage-independent growth of the HEC-1-A cell.