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Significant correlations between acute post-race changes in the levels of serum uric acid, suPAR, and IL-6 also support a synergistic relationship between the status of inflammation and generation of oxidative stress [31].
These results support a synergistic effect for the actions of IGF-1 and Dex on basal cell activity.
Although our results are not fully conclusive in this respect, they support a synergistic role of TRAIL, JNK and Bim in APAP-induced liver damage.
In conclusion, our results do not support a synergistic effect of the combination of octreotide and TMX as suggested in breast cancers and reinforce the lack of efficacy for hormonal therapy in HCC, even for combination.
The median PFS of 33 weeks observed in patients treated with the combination compared with 30 weeks for those treated with sorafenib alone (P=0.109), does not appear to support a synergistic effect of sorafenib and IL-2 in the overall study population.
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The pseudocapacitance property supports a synergistic effect on both double-layer capacitance and pseudocapacitance [24, 25].
The effect on apoptosis was amplified by combining the inhibitors, supporting a synergistic effect on viability.
Our GRN also supports a synergistic interaction between Pou-domain containing transcription factors and bHLH proneural proteins in the activation of several target genes.
This results in both sexual and aggressive deficits even though two-thirds of the VNO remains unperturbed, further supporting a synergistic model of pheromone signaling.
All genotypes respond to tZ by increasing in diameter but notably the ant-9 cycdoubleouble mutant remains thinner than other genotypes at higher tZ concentrations (1000 ng/µl; Fig. 3D), supporting a synergistic interaction between ANT and CYCD3 1 and implying that these factors independently contribute to radial cell division activity in the cambium.
Furthermore, our analysis predicts Creb1, Crebbp, and Yy1 as the most likely candidates for dorsally expressed Ngn2 co-factors, and supports a synergistic interaction between Pou-domain containing transcription factors and bHLH proneural proteins in the regulation of common target genes, which is consistent with previous studies [ 12].
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