The North Korean education system has been in ruins since a famine in the 1990s deprived most schools of heating fuel, adequate food rations and school supplies, deprivations that some analysts believe continue today.
"Nutrient supply and deprivation is becoming potentially the next big wave," said Dr. David Schenkein, chief executive of Agios Pharmaceuticals, a company formed two years ago to develop drugs that interfere with tumor metabolism.
Malignant cells have developed adaptive mechanisms to survive under extreme conditions of tumor microenvironment, such as restricted oxygen supply and nutrients deprivation.
We have to make up our stock; to again create the guarantee fund, which shall insure us against any new calamities against some deprivation of supply as sudden and as unlikely as an American civil war would have seemed five years ago.
A breast tumour rapidly outgrows its blood supply, leading to glucose deprivation and hypoxia.
Results Models including person level information (age, sex, and ICD-10 codes diagnostic recorded) and a range of area level information (such as socioeconomic deprivation and supply of health facilities) were most predictive of costs.
Progressive build-up of A β in and around vessels induces alteration in the BBB permeability, which chronically limits blood supply and results in deprivation of oxygen and nutrients 12, 13.
These results indicated that the excess risk of ESRD incidence observed in the unadjusted analysis was explained in a great part, but not entirely, by age, sex, healthcare supply and socio-economic deprivation taking into account rural/urban typology.
For 2002, household head characteristics were retained at the first step (F = 2.95, p = 0.007), but household expenditure, the information deprivation index, supply interruptions and cholera-affected provinces were discarded in in the subsequent four steps (F = 1.57, 2.01, 0.62, and 5.65; p = 0.14, 0.16, 0.68 and 0.02, respectively).
