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That makes housing supply dependent on a few well-capitalised developers.
With so much supply dependent on so few companies and facilities, safety problems that arise anywhere in the system can result in enormous disruptions.
For each product there is also a "supply function" that expresses the quantities producers will supply dependent on their costs of production, the prices of productive services, and the level of technical knowledge.
What was once a city of interconnected lakes and more than 60 rivers is now a dusty megalopolis with barely a clean stream or pond, with a broad downtown plaza sinking into what was once a wetland, and with a water supply dependent on sources 250 miles away.
Also, clinical data indicate the relationship between the presence of this supply dependent state of oxygen consumption and increased lactate levels similar to animal studies [11].
In addition, Friedman et al. [13] showed that this phenomenon is present in the early resuscitation phase of critical illness, suggesting that resuscitation resolves a state of supply dependent oxygen consumption and thereby the hyperlactataemia.
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This has been confirmed in an experimental study of cardiac tamponade by Zhang et al. [10], which showed that resolution of the supply-dependent state of oxygen consumption by resolving the tamponade was associated with an increase in oxygen consumption to baseline levels and normalisation of lactate levels.
In addition, using NIH3T3 cell line, Gilles A's finding suggested that PKM2 could regulate cell proliferation, cell growth and apoptosis in a glucose supply-dependent manner [50].
In this investigation, baseline markers of global perfusion (central venous pressure, mean arterial pressure, and central venous oxygen saturation) were near normal prior to initiation of either resuscitation bundle, suggesting a better resuscitated, less supply-dependent population than the original early goal-directed therapy study.
This has been confirmed in an experimental study of cardiac tamponade by Zhang et al. [ 10], which showed that resolution of the supply-dependent state of oxygen consumption by resolving the tamponade was associated with an increase in oxygen consumption to baseline levels and normalisation of lactate levels.
11 The transportation, storage, and distribution of a great part of the nation's food supply is dependent upon a continuous, and dependable supply of ice.
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