Proving the efficacy and corresponding mode of action of herbal supplements is a difficult challenge for evidence-based herbal therapy.
Given the thousands of orally ingested products on the market (RX, OTC, and dietary supplements), it is difficult to quantify the prevalence of phthalate-containing products.
Moreover, the low proportion of women who took prescription calcium tablets (6%), containing a four times higher dose of calcium than in regular multivitamin dietary supplements, made it difficult to detect modestly strong associations with calcium tablet use specifically.
These data have been added to the revised manuscript as Figure 1 figure supplement 4. 6) The HA blot in Figure 3 figure supplement 2B is difficult to interpret.
The extra help may provide a valuable supplement to a difficult or crowded course, but it could also leave students with a false sense of mastery.
Capturing dietary supplement intake is difficult when the participant provides insufficient detail.
6) The HA blot in Figure 3 figure supplement 2B is difficult to interpret.
4) The experiments described in Figure 5 figure supplement 2 are difficult to interpret and are not helpful.
Other significant changes: We realized that the targeting vector design presented in Figure 1 figure supplement 1A was difficult to interpret, and did not adequately explain how the Southern blot screening strategy worked.
With so little known about supplements, it can be difficult, particularly for teenagers, to make wise decisions.
