This is an initial brainstorm, possible directions with which to change or supplement the Reference Book model of legal resources.
One cost-efficient approach to address this issue is to consider re-sequencing a small number of individuals from the analysis cohort to supplement the reference panel.
The electronic search was supplemented with the reference lists of identified papers, reviews and opinion pieces.
Results were supplemented using the reference lists of the articles identified and papers from the reviewers' collections.
Gsnap supplements the reference sequence with a list of all known HSVs and their corresponding homoeoloci.
The second strategy is to consider all possible phasings of variants that can occur in the same sequence read and either supplement the reference genome with these haplotypes [ 20] or use this information during alignment with a polymorphism-aware aligner, such as GSNAP [ 21, 22].
To supplement the global search, reference lists provided by country and regional teams were included to strengthen the inclusiveness of the literature scoping (see Additional file 2 for the list of databases searched by country, regional and global research teams).
For any external information you use to supplement the article, please reference it to allow for easy verification.
This article, written by Matt Wells, was published online by BBC's Today Programme on March 19th, 2011, to supplement the radio broadcast referenced above.
To supplement the search, we scanned the reference lists of included studies and searched the authors' personal files.
