Exact(1)
These are the ICD-9-CM codes that make up the four supplementary subgroups by additional diagnosis included patients who had at least one ICD-9 coding for the following diseases: Upper respiratory infection (460, 462, 464, 465, 466, 487), Lower respiratory infection (480, 481, 482, 483), Septicaemia (038.x), Heart Failure (428) [ 14].
Similar(59)
Finally, we did a supplementary subgroup analysis in which we compared the effect of acupuncture on the basis of whether or not the placebo acupuncture penetrated the skin.
In order to better visualize certain key effects from these main analyses, a supplementary subgroup classification was conducted on the older participants.
We performed supplementary subgroup analyses to examine the effect of sirolimus by type of donor (living v dead) and the use of antibody induction therapy (yes v no).
To check for bias introduced by the inclusion of FMU women giving birth in 2004, supplementary subgroup analyses were performed on 2004 data and main data, respectively.
Supplementary subgroup analyses found a statistically significant difference in effect of acupuncture between the two trials using non-penetrative placebo needles (pooled standardised mean difference 0.07, −0.18 to 0.32) and the 10 trials using penetrative placebo needles (pooled standardised mean difference −0.21, −0.30 to −0.11) (P=0.04).
A careful examination of the taxonomic distribution within the subgroups (supplementary fig. S2, Supplementary Material online) revealed that only 2 Rhizobium/Agrobacterium complete genomes contain the aio genes although nearly 30 genome sequences are available at NCBI.
In particular, the first and second generation COCs containing 20 25 µg EE showed less suppressive effects on total T than did the other subgroups (Supplementary data, Table SII and Supplementary data, Fig. S2).
We next assessed mass spectrometry-minimal methylation classifier (MS-MIMIC) performance against Illumina 450k methylation microarrays in an independent validation cohort of 106 medulloblastoma DNA samples (Fig. 1c) containing all four medulloblastoma subgroups (Supplementary Table 1).
Further examination of our copy number data set revealed rare examples of chromothripsis across subgroups (Supplementary Fig. 40), with only chr8 in Group 3 demonstrating statistically significant, region-specific chromothripsis (Q = 0.0004, false discovery rate (FDR -corrected Fisher's exact test).
Consistent with findings of previous studies of slime from different onychophoran subgroups (Supplementary Table 1), our multi-scale approach clearly indicates that mechanical and chemical factors act synergistically to promote slime fibre formation and regeneration.
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