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Following the World Summit for Children in 1990, Burkina Faso and many other countries around the world made a commitment – which was renewed in 2000 – to eliminate MNT through routine immunization activities for pregnant women and children, combined with supplementary rounds of immunization to protect women of childbearing age.
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It has therefore been suggested that dry season MDA interventions should be supplemented with a correspondingly timed supplementary round of IRS to minimize human re-infection rates 38 and that radical cure should be followed by a period of prophylaxis at least as long as the maximum life span of the mosquito.
Nonetheless, with the funds available, the Ministry of Health was supported in conducting two rounds of supplementary immunization against diphtheria.
The funds will cover more than 5 million doses of oral polio vaccines for two rounds of Supplementary Immunization Activities for November and December.
As recommended by the World Health Organization, additional rounds of supplementary measles vaccinations and services will be necessary to ensure the sustained reduction of infant and maternal deaths.
This counterbalance retention of gene function in successive WGDs observed in plants is in contrast to mammalian diploidization-resistant regulatory genes that have be shown to be retained as pairs after each rounds of WGDs (supplementary figure S6 A, Supplementary Material online, red dashed arrows), Murat et al. 2010.
These tumors were then subjected to further rounds of transplantation (supplementary material Table S1).
In addition, two clusters of C. elegans-specific SNF2-like genes and Helitrons in the PIF1 subfamily were found on the terminal regions of chromosomes V and II, respectively, suggesting that these genes might have been generated by a few rounds of gene duplications (Supplementary Figs S1C and G; see the figure legend).
In addition, two months later, two rounds of house-to-house supplementary immunization activities (SIAs) were conducted in 19 townships of North Shan State in Myanmar, covering 233,000 children <6 years of age.
This set was further reduced to fifteen clones after F1 generation animals were tested in three additional rounds of screening by an independent investigator (Supplementary Table I).
Vertebrates have an average number of 24 KLF/SPs, likely due to the 2 rounds of whole genome duplication (WGD) in the vertebrate stem lineage (supplementary fig. S5, Supplementary Material online).
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