In response to patients' pleas, nine supplementary resolutions were adopted, including provisions for living stipends and patient work, improvement in living conditions, promotion of research, and installation of rehabilitation facilities.
In addition, the structure of the metal-free TCC (TCCApo) was refined to 3.15 Å resolution (Supplementary Table S1; see also Supplementary Figure S3 for the final and simulated annealing omit electron density maps of the refined models).
We determined the crystal structures of the m3MST complexes with 1 and 3 at high resolution (Supplementary Table S3).
We applied 96 mV to the galvo mirror (4 steps), resulting to 5-ms time resolution (Supplementary Fig. 11b).
We obtained crystals of PCNA dsDNA complex with one PCNA trimer per asymmetric unit and diffracting to 2.8 Å resolution (Supplementary Table 1).
Using our modified library generation method, we generated genome-wide DNA methylomes for human sperm, oocytes, 8-cell embryos, morula, ICM, and 6-week embryos as well as the full-term placenta at single-base resolution (Supplementary Table S1).
Also, RvD1, PD1, and AT-LXA4 at 300 ng per mouse (i.e., 12 μg kg−1) each reduce the Ri, whereas RvE1 accelerates the onset (Tmax) of resolution (Supplementary Table 2).
DprE1-PBTZ169 crystals diffracrystals1.9 Å resolution (Supplementary Table 3).
Reduced Mms4 levels induced by tetracycline addition correlated with impairment in the late resolution (Supplementary Figure S2A).
The final model, refined at 1.9 Å resolution (supplementary Table S1 online), contains residues 237 414 of G2P.
