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We have chosen to project the puppies as supplementary observations on the PCA plane defined by the eight healthy and the 11 GRMD adult dogs of our previous study [ 3].
The individuals were projected, as supplementary observations, on the reference PCA plane that we previously defined in [ 3], using eight healthy and 11 GRMD adult dogs, and the seven following variables: stride length/HW, stride frequency, total power, medio-lateral, cranio-caudal, dorso-ventral parts of the total power, and regularity.
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Although the data set and the length of the alignment per window are both greatly reduced, the results, shown in supplementary table S-4 (Supplementary Material online), are consistent with our previous observations on the whole TE data set: the stronger female effect on the RR/GC* correlation outside of the telomeric regions.
Interestingly, thymidine also induced the expression of p53 in both HCT116 and RKO cells (Supplementary Figure S1B), in agreement with previous observations on cellular responses to thymidine.
The observed clustering is in agreement with a number of independent genotypic and phenotypic observations on the strains (Rademaker et al., 2007; see Supplementary Table 1) supporting the robustness of the method developed in this article.
The observations on EGFP-Irgm1 have been confirmed in Raw264.7 macrophages (Supplementary Figure S1).
Since both yeast proteins are required for ribosomal RNA biogenesis and essential for viability in yeast, our observations on both genes are probably significant (see the legend of Supplementary Table S1 for other discrepancies).
A model that synthesizes and explains the entirety of our observations on Notch-Su(H) regulation of cardiogenesis is presented in Fig. 8B and supplementary material Fig. S10A-D.
12 Observations on a disaster.
But are such observations on target?
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