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It is shown in Supplementary Materials (Supplementary Lemma S3) that there is no advantage to considering SD + CD paths with gain and loss of the same chromosome.
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The proof of Lemma 2.1 is supplementary of Theorem 3 in [28], which helps the readers to understand that (2.2) holds.
See the Supplementary Material for proofs of Lemma 1 and Theorem 1. Similarly to Theorem 1, we can show that any pairwise tree alignment that does not take joining nodes into account, can also be computed in this time.
For the proof of Lemma 2 please see Supplementary Appendix Proof of Lemma 2. L emma 3 Every conflicting simple cycle in GC includes exactly one odd length simple cycle in GF.
(The limit (Q N x ) i, 1 → 2 / i as N x →∞ was noted by Fisher and Wright (Ewens 2004, eqn (1.56)).) We show in lemma 2 of the electronic supplementary material, that assuming Q N x (i ) ≈ (2 / i ), the probability β that a site has an observable heteroplasmy is closely approximated by 2 α ln(θ−1−1).
In lemma 1 of the electronic supplementary material, we show that Pr (n k = i | n g − 1 = 1 ) = (P N x ) i, 1 (g − k − 1 ), which is the ith entry of the leading column of P N x (g − k − 1 ).
This is justified by the following lemma, whose proof stands in the Supplementary Material.
We have the following lemmas, which we prove in the Supplementary Appendix.
But the argument for the lemma is unconvincing.
A theorem, perhaps, a lemma or even just a corollary.
"Concerns about religious supplementary schools.
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