When applied to all 3937 intergenic regions, the HMM predicts only five additional hrp boxes with confidence (Supplementary Table S3; Supplementary Fig. S2).
Combining the results of these four analyses, mass spectrometry identified a total of 324 proteins with >95% confidence (supplementary tables S1 and S2, Supplementary Material online).
The overall preamplification efficiency was 101.4% (± 3.5%, 95% confidence) (Supplementary Figure 1).
In 1988, the International Committee of Medical Journal Editors (ICMJE) warned against sole reliance on NHST to substantiate study conclusions and suggested supplementary use of confidence intervals (CI).
To verify the PPI data obtained by YTH screening, 18 pairs of candidate interactions with high confidence (Supplementary table 6) were analyzed by MSIP.
Thirteen of the 16 sorghum regions with putative segmental maize deletions were within these bounds; the remaining three regions had an average number of maize best blast hits below the lower bound of this confidence interval (supplementary table S5, Supplementary Material online).
Bottom, the total number of pairs with a median association score bigger than that of the negative control at different statistical confidences (Supplementary file 1 ).
However, for these and other parameter combinations, the number of unselected regions misclassified as constrained decreases dramatically after imposing a 95% confidence cutoff (supplementary fig. S3 B, Supplementary Material online).
Most of the improvement is in the crucial high confidence predictions (Supplementary Fig. S3).
The adjusted association of urinary albumin-creatinine ratio with cardiovascular mortality seemed flat for both men and women with wide confidence intervals (supplementary fig 3, C and D).
