There were no significant differences in survival between our patients with mutations Arg719Trp, Gly716Arg, Ile736Thr (figures Ia c and table A in online supplementary file) and Gly768Arg (table A in online supplementary file) compared with those from the literature.
If this were true, the small measured 2 8% contribution of blood lactate oxidation to total TCA cycle flux over the range of brain lactate level studied by Boumezbeur et al. (2010) defines a situation where lactate is a minor, supplementary fuel compared with blood-borne glucose that accounted for 92 98% of TCA cycle flux.
The migrating ability of OCUM-12 cells was increased in the presence of TGF- β1 (Supplementary Movie 1), compared with the control (Supplementary Movie 2).
The Chinook salmon SDR was extended to 16,722 bp (supplementary file S2, Supplementary Material online), compared with the previously published 12,567 bp OtY3 contig.
As noticed by Schrimpf et al. (2009), mRNA abundance data are relatively poorly correlated between nematodes and flies and with the ERs (supplementary table S3, Supplementary Material online) compared with the protein abundance data (table 1).
Membership of each cluster was also quite similar (Supplementary Fig. 11), compared with that of genotyped SNPs (Supplementary Fig. 12).
For example, the incidence of severe AEs during the first 3 months of treatment was 2.4% (supplementary table 5) compared with 3.3% in patients receiving 12 months MR prednisone treatment (supplementary table 6).
These quality issues can be seen clearly in the FastQC plots, shown in the Supplementary Figure S1, compared with the much higher average quality of the post-filtered data, as shown in Supplementary Figure S2.
Extensive simulation results are shown in Supplementary Fig. 1 compared with measured data.
Khan won 44% of first preference votes under the supplementary vote system, compared with Goldsmith's 35% – almost exactly the same proportions as Labour and Conservative parliamentary candidates had taken in London at the general election.
