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While considering scaling effects due to sequencing depth, our results agree well with these findings in that the AS rate is very low compared with that in non-yeast Ascomycota (see Supplementary Calculation S1).
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GPS calculated the potential energy storage of the resilin and provided the supplementary calculations.
Supplementary calculations on larger supercells for the Ag S doping configuration indicate that the single (Ag, S) dual-dopant pair behaves in a similar way to that in the small supercells with lower local atomic relaxation, weak band splitting and reduced band gap.
Both supplementary calculations are based on differences in results reported by the same research group [ 13].
Supplementary calculations of the area under the curve for a one-sided normal distribution indicates that 99.999999% of the probe signals would be below 343 MFI (mean plus 5.612 times the s.d).
Supplementary cost calculation guidance suggested overall savings to the NHS from a "switch" of activity from Stimulated IUI (S-IUI) to U-IUI, which was also recommended [ 2].
For supplementary statistical calculations, we used the MedCalc® version 5.00.017 computer software (MedCalc Software, Mariakerke, Belgium).
Evolutionary divergence between sequences of 17 STs was received by pairwise distance calculation (Supplementary Material, S2 and S3).
To statistically validate the predictions, we computed the frequentist coverage probability for each calculation (Supplementary file 1E ).
We also checked the correlation between the two exons by using Fisher exact test (as in [ 21], See supplementary for the calculation and discussion of the statistical test).
Unlike sparser networks such as interaction networks, PSNs are frequently close to complete, often requiring storage and management of large quantities of data, and fast calculation (Supplementary Table S2).
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