Supplementary material Supplementary material Supplementary material Supplementary material Supplementary material.
Supplementary Material Supplementary Material Supplementary Material Supplementary Material.
Supplementary Materials Supplementary Materials.
Despite the modelling analysis suggesting that these increases in condom use partially caused the observed decline in HIV prevalence, it cannot directly attribute the CCU changes to Avahan without additional information (Supplementary material, Background section,).
JP provided background material.
Confocal fluorescence microscopy confirmed that the protein is located in mitochondria irrespective of the cellular age and the genetic background (supplementary material, Supplementary Figure 2).
Gas1 −/− mouse embryos present with small eyes and reduced body size (Allen et al., 2007), reminiscent of some gnz mutants in C3H/HeJ background (supplementary material Fig. S1A,B).
CTCF expression was able to partially rescue both, lethality (around 75% of mutant larvae pupariate, data not shown) and, importantly, developmental delay (pupariation was clearly advanced by CTCF expression in the CTCF y+6 mutant background, supplementary material Fig. S1).
While generating the sub-congenic strains, heterozygous phenotypes (shaky-head behavior in Celsr1 Crsh /+ and looped tail in Vangl2 Lp /+) became less penetrant on the C3H/HeH background (supplementary material Table S2).
Overexpression of the small leucine-zipper-type microProtein ZPR3, which largely reduces the activity of HD-ZIPIIIs, led to a further enhancement of the senescence phenotype, which was ameliorated in the wrky53 mutant background (supplementary material Fig. S3).
