(Interested readers may wish to read the supplementary document Background Assumptions for Plantinga's Account).
Despite the modelling analysis suggesting that these increases in condom use partially caused the observed decline in HIV prevalence, it cannot directly attribute the CCU changes to Avahan without additional information (Supplementary material, Background section,).
Confocal fluorescence microscopy confirmed that the protein is located in mitochondria irrespective of the cellular age and the genetic background (supplementary material, Supplementary Figure 2).
Having a closer look at the residuals of contingency tables suggests that almost half of the candidate genes have an unexpectedly low number of synonymous substitutions compared with the genomic background (supplementary table S5, Supplementary Material online; Fisher's exact test P < 0.001).
All modifications were performed in the S288C background (Supplementary file 2).
Numbers indicate the fold change in activity caused by a mutation in a certain background (Supplementary file 2B F ).
At Day 40, 746 genes were increased and 715 genes were decreased in DR in the Canton-S background (Supplementary Figure 1).
Gas1 −/− mouse embryos present with small eyes and reduced body size (Allen et al., 2007), reminiscent of some gnz mutants in C3H/HeJ background (supplementary material Fig. S1A,B).
Our data show that, except for 5, all NCAAs led to sfGFP expression significantly better (1.8 3.9-fold 1.8 3.9-foldckground (Supplementhan Figure 4).
Targeted deletion of a genomic fragment containing exon 2 of ROCK2 gene was accomplished by homologous recombination in C57BL/6 genetic background (Supplementary Figure 1).
CTCF expression was able to partially rescue both, lethality (around 75% of mutant larvae pupariate, data not shown) and, importantly, developmental delay (pupariation was clearly advanced by CTCF expression in the CTCF y+6 mutant background, supplementary material Fig. S1).
