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Supplementary analytical frameworks that enable communities to undertake analyses of cultural assets and liabilities to enhance local understanding of how cultural belief systems influence HIV risk-taking are also needed.
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All supplementary chemicals were of analytical grade and all solution mixed by deionized water.
Analytical ultracentrifugation (supplementary information Fig 1 online) and nano-flow mass spectrometry of the intact complex (Fig 1B) showed that human GINS is a heterotetramer with 1 1 1 1 stoichiometry.
The homodimeric form of RecX appears to be an artefact of crystallisation because we could not detect it in solution using size-exclusion chromatography, homo-bifunctional chemical crosslinking (not shown), or sedimentation velocity in an analytical ultracentrifuge (Supplementary Figure 1).
Mineralogical and chemical studies were carried out on sediment samples from the floors of the Dinaledi and Dragon's Back chambers (Facies 2; Unit 3) to assess the nature of the sediment encasing the Dinaledi fossils and to determine whether these chambers were connected at the time of deposition of Units 2 and 3 (see Supplementary file 1 for analytical results).
Supplementary data Synthetic procedures and analytical data for compounds 1 and 4.
If any imbalances of characteristics between the two groups are identified, these will be adjusted for in the main analytical modelling as supplementary analyses.
For further details on the analytical model, see the Supplementary material.
The main investigator (first author) also wrote supplementary field notes and appended preliminary analytical notes to each interview transcript.
Ultimately, supplementary data, replication datasets, or multiple analytical approaches must be used to filter the results down to a manageable number of the 'most likely' genes.
A number of supplementary analyses were conducted in strata of analytical population.
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