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The results for these supplemental outcomes are published elsewhere.
We will define a priori core outcomes and supplemental outcomes of paediatric asthma, including exacerbation, healthcare use and pulmonary function.
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Studies were included if they met the following criteria: the study design was a prospective cohort study; the exposure of interest was intake of dietary magnesium or total magnesium (dietary and supplemental); the outcome of interest was incidence of type 2 diabetes; and the risk estimate of type 2 diabetes related to magnesium intake and associated 95% CI were reported.
No significant changes were observed in such components of experimental design as "independent variable/treatment," "quantity measured," and "expected outcomes" (Supplemental Figure S3).
A series of restricted models using the same specifications as the basic models, but with data on only those households included in the full models, yielded similar results to the basic models for all four outcomes (Supplemental Table 5).
The experimental design score was based on seven components that included appropriateness (the match between the hypothesis and the proposed experiment), identification of experimental system, treatment, control group, assay, quantity measured, and expected outcomes (Supplemental Table S3).
When we re-estimated differences between groups using two different matching estimators, which make fewer assumptions about the relationship between the adjustment covariates and household environmental group, we obtained results consistent with our primary analysis for all outcomes (Supplemental Table 7).
Objective: To examine the effect of an inpatient pulmonary rehabilitation program on functional outcome, supplemental oxygen use, quality of life (QOL), and rehospitalization.
13613_2015_101_MOESM1_ESM.pdf Additional file 1. Supplemental Methods and Outcome table.
The same comparison was repeated with the regulons of the two other major nucleoid proteins H-NS and Fis [72] with a very similar outcome (Supplemental Fig. S1 B, C & Tables S10 to S14).
In a research context, PROs have become an important outcome supplemental to clinical parameters (e.g., survival, toxicity ratings).
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