The Supplemental Figure S1 data will be very disturbing, if one's only experience with intercalators has been to use a fixed amount of intercalator to quantitate an unknown amount of duplex DNA.
More than 99.75% coverage of each genome was obtained by assembling the raw sequence data from the titration and supplemental sequencing runs (these data will be referred to as the combined run data; see Methods), to an overall average depth of coverage of 24.6× in Nandina and 17.3× in Platanus.
In addition, three hundred pulmonary fibrosis patients who do not use daytime supplemental oxygen will be recruited to participate in a longitudinal, pre-/post study in which patient-reported outcome (PRO) and activity data will be collected at baseline, immediately before daytime supplemental oxygen is initiated, and then once and again 9 12 months later.
Furthermore data will be assessed after 12, 24 and 36 months for a supplemental investigation.
These data will be linked and pseudo-anonymised to just NHS number: A national, unique, ten-digit identifier that makes it possible to share patient information across the whole of the NHS) then supplemental data about specific diagnosis and laboratory advice will be added from hospital pathology laboratory records [ 20].
Due to the nature of supplemental materials, it is probable that some supplemental data will not appear explicitly in the publication.
Patients with pulmonary fibrosis, informal caregivers of pulmonary fibrosis patients and practitioners who prescribe supplemental oxygen will be interviewed to gather data on perceptions of how supplemental oxygen impacts patients.
According to court papers, supplemental claim forms will be sent out today to 8,324 people.
2) In keeping with eLife's policy to minimize supplemental data, it will also be necessary for you to insert most of the supplementary figures into the body of the manuscript, editing the text accordingly.
Supplemental survey data collection and management will be conducted according to the standard procedures used for the standard bi-annual surveys and is described in above.
