The annotated slides were made available to students after class (Supplemental Figure S2).
The expression of some of these genes was down-regulated at 6 and 8 hours [Additional file 1: Supplemental Table S1, Class II].
All of them were induced by late As III) stress [Additional file 1: Supplemental Table S1, Class II], which strongly suggests that arsenite oxidase activity is specific to late exposure.
Reduced occurrence of stepping errors in the rapid step test was related to small molecules within glycerophospholipid, carbonyl and carboxylic acid metabolite classes (Supplemental Table 5).
Indeed we made a new biological observation: we could statistically separate the branching points of the 4 PN classes (Supplemental Data), demonstrating the high degree of spatial stereotypy of PN axon branching patterns.
To further address the possibility that hypnotic-associated hazards were due to use of hypnotic drugs by patients with a greater burden of disease, so that elevated risks of death might be attributable to comorbidities rather than to hypnotic medications, we conducted analyses within subgroups of hypnotic non-users and users defined by diagnoses in specific disease classes (supplemental table 7).
This resulted in 41 distinct bioinformatically derived classes, containing at least one CpG, based on bioinformatic attributes [for the distribution of CpG loci by bioinformatically derived class, see Supplemental Material, Table 2 (http://dx.doi.org/10.1289/ehp.1103927)].
This file contains all the Supplemental Tables including functional classes over-represented in the set of genes associated with SE-IPACs and A-IPACs.
To investigate the relationship between repeat element methylation and gene-associated methylation, we clustered the 26,486 autosomal CpG loci interrogated on the Infinium HumanMethylation27 BeadArray into 16 methylation classes based on their methylation pattern using an RPMM [for the heat map of the 16 classes, see Supplemental Material, Figure 1 (http://dx.doi.org/10.1289/ehp.1103927)].
The VM was introduced as an optional supplemental resource to an entire class of students during the pilot period.
