When the subjects laughed with the recorded laughter, the anterior supplemental motor area, near the brain's top, became active.
Walther et al. linked PMR to CBF of the supplemental motor area, suggesting disbalanced motor control in MDD [ 77, 78].
Please see below for the edited text passages: Results, Schema consolidation: "Across both days, retrieval was associated with increased BOLD responses in bilateral lingual gyrus, superior occipital gyrus, cuneus, left supplemental motor area, and right parahippocampal cortex".
This specific comparison yielded increased activation in bilateral lingual gyrus, superior occipital gyrus, cuneus, and left supplemental motor area on day 1 relative to day 2 (day 1 > day 2; Figure 3B; Table 1, middle part).
Across both days, schema retrieval was associated with increased blood oxygen-level dependent (BOLD) responses in bilateral lingual gyrus, superior occipital gyrus, cuneus, left supplemental motor area, and right parahippocampal cortex (day 1 & day 2; Figure 3A; Table 1, upper part).
The motor network comprised of left primary motor cortex (x = −40, y = −22, z = 58), left supplemental motor area (x = −4, y = −2, z = 54), and left (x = −56, y = 4, z = 38) and right (x = 54, y = 4, z = 44) premotor cortex.
During lexical decision, words with low vs. high lexical frequency increased activation in left frontal, anterior cingulate, supplemental motor area (SMA), and pre-SMA regions; while words with high vs. low syllable frequency increased activation in a left anterior inferior temporal region.
In these studies, mental processes that require subvocal rehearsal preferentially activated the left prefrontal cortex, the bilateral occipital cortex [ 36], Broca's region, the premotor cortex, the supplemental motor areas, the left posterior parietal cortex [ 37], and the cerebellum [ 38, 39].
These supplemental rest areas are very small-sized resting facilities located between the larger regular rest areas, which is a unique design.
Outside of visual areas, Obata, et al, [45] also showed different BOLD responses in primary motor cortex versus supplemental motor areas (SMA), with a much smaller undershoot within the SMA.
