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AF contributed to the conception and design of the study and the manuscript, supervision of analysis of the data and drafting the manuscript.
RB: conception and design, obtaining of funding to conduct the study; supervision of analysis and interpretation of data; drafting of the manuscript and revising it critically for important intellectual content; writing and final approval of manuscript.
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SM carried out biostatistical analysis, supervision of data analysis, and data interpretation.
AM contributed with ideas for data analysis and supervision of data analysis; and contributed in writing manuscript.
MLJG participated in the conception, study design, statistical analysis, coordination, supervision of laboratory analysis and manuscript writing.
MJ: study conception and design, data collection, supervision of data analysis, drafting of manuscript; SS: data collection, data analysis, and drafting of manuscript; MA and JP: study conception, data collection, and interpretation of results.
Further to this, rigorous analysis procedures will be followed by the researchers including regular supervision of the analysis by experienced qualitative researchers in order to avoid the participant's views being misrepresented and to uphold anonymity of data by considering the multiple clues to identity present in individual narratives.
We are very grateful to Dr. Giovanna Chiorino (Fondazione Edo ed Elvo Tempia, Biella, Italy) for supervision of microarray analysis, to Dr. Patrizia Vaghi (University of Pavia, Italy) for confocal microscope analysis and to Dr. Pierre Roux (CNRS FRE2593, France) for the EGFP-C1-Rnd3 plasmid.
NS contributed to study conception and design, supervision of research, analysis and interpretation of data, drafting and critical revision of the manuscript for intellectual content, and statistical analysis.
Formulation of research questions, supervision of data analysis and interpretation of results.
TAP participated in the supervision of data analysis and manuscript preparation and critical revision.
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