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BK supervised the cell biology work.
AD and AF supervised the cell culture experiments and microarray experiments.
KFW supervised the cell culture work and contributed to the analysis of the fly data.
Wei Guo supervised the cell culture experiments in the early stage and purchased the drugs and antibodies.
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The Roths were Jewish intellectuals who had money — his father was a doctor who supervised the sickle cell clinic at Mount Sinai Medical Center, his mother a classical musician — and Marco was their pampered only child.
JJ and TH designed and carried out experiments and wrote the manuscript; AFN designed and carried out experiments; TK performed experiments; MM designed experiments; MB supervised the B cell part of the project; JP and KH contributed to experiments; TH designed the shRNA cloning strategy; JM supervised the project and contributed to writing the manuscript.
ASVCR: Performed the study and prepared the manuscript; SGR: Provided assistance in the investigation on cell lines; PPB: Provided cell lines and supervised the study on cell lines; ARR: Supervised the work, provided the grants for the study, evaluated the data, corrected the manuscript for publication and coordinated the study.
JAK: performed and supervised the mouse ES cell work and the generation of the transgenic mice as Director of the Animal Transgenic Facility at Brown University.
JRS supervised the isolation of the cell lines and performed all karyotyping.
LSG supervised the establishment of MCA cell lines, helped with the tissue culture work and with drafting of manuscript.
KC developed the concept of the study, implemented the SA-β-Gall and other assays for identification of senescent cells, supervised the experimental work and the interpretation of results and contributed to writing the manuscript.
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CEO of Professional Science Editing for Scientists @ prosciediting.com