Additional file 7 shows a comparison of unsupervised hierarchical clustering with supervised subtype assignment and single marker scores for GEICAM/9906.
Strengths of the study were the individual random assignment, supervised supplementation, menstrual period monitoring combined with ultrasound to date pregnancies, and standardized measurements of glucose tolerance during pregnancy.
A potential limitation of this trial is the unblinded design, although it is impossible to keep assignment to supervised training hidden to both patients and physicians.
Additionally, the supervised PLS-DA analysis with assignment of the groups based on disease status and sex revealed a sex dependent clustering of the pneumonia group, which was not present in the controls (Fig. S3).
For validation data, we used supervised clustering based on the assignment of samples to the cluster with the closest centroid.
In most cases, a supervised binning of sequences according to an assignment to predefined taxonomic categories is performed.
On the other hand, Dave and coworkers [ 30] based their supervised Bayesian method on independent expert pathology assignment of cases to the BL/DLBCL classes, and created a classifier based on 217 genes.
The subtypes of these samples were assigned using PAMR, and results were cross-validated extensively using supervised hierarchical clustering and PCA to ensure the re-assignments of these samples to subtypes are consistent with the previous prediction.
The three genomes of OV14, 1021 and C58 were compared by using evolutionary genealogy of genes: Non-supervised Orthologous Groups (eggNOG) assignments.
Qualification as an NMP requires students to pass a number of non-compensated elements of assessment including examinations, portfolio assignments, objective structured clinical examinations, medically supervised practice [ 29] and an evidence based therapeutics poster presentation.
Interestingly, 8 years later, the 2013 edition of the campaign proposed to revisit GO assignment tasks with different outcomes: this time, supervised systems that exploit curated data outperformed dictionary-based approaches (11).
