It is a change in the sense that it supersedes the effective moratorium".
Ongoing research and programme experience have helped to define new pMTCT approaches and the strategies reviewed have largely been superseded by more effective and more resource-intensive clinical options.
Dopamine antagonists, which have long been the treatment of choice for CINV, are being superseded by the newer more effective and better-tolerated agents, and it has been recommended that their use should be reserved for patients who fail to respond to serotonin antagonists (Markman 2002).
He took his sister Hannah with him and reached India at a vital moment when effective government by the East India Company was being superseded by that of the British crown.
Dopamine agonists were the first effective medical therapy for acromegaly, but have since been superseded by somatostatin analogues.
Mr. Moak said the contract agreement would become effective when the combination of Delta and Northwest closed, unless the agreement was first superseded by a joint collective bargaining agreement between Delta management and the pilots of Delta and Northwest.
A third modality, scanning laser polarimetry (GDx and its derivatives, Carl Zeiss Meditec, Dublin, California, USA), is as effective in terms of glaucoma 'classification' as HRT and OCT, but has largely been superseded by OCT technology in terms of clinical practice and in active research.
Cash, frankly, has superseded class.
Business has superseded security concerns".
Harvey nickel-steel armour superseded earlier types.
