Sentence examples for superior replication from inspiring English sources

Such a difference could not be explained by the superior replication capacity of the mutant virus, since NS1 protein deletion abrogated the multicycle replication.

The process achieves superior replication of design specifications compared to all other 3D printing technologies and so is a promising methodology for producing scaffolds with complex 3D microstructures for tissue engineering.

Subsequently, M184V develops because of an independent substitution within the same triplet codon (ATG to GTG), and viruses containing M184V then outcompete those containing M184I because of superior replication fitness.

39 Detectable induction of type III IFNs was less frequent in HFLC infected with the JC1G reporter virus, possibly reflecting the superior replication efficiency of J6JFH Clone 2 relative to JC1G.

One possible explanation is that there was a large, geographically dispersed pool of mutated viruses, and that vaccination pressures against more severe strains exploited the superior replication and transmissibility of smoother and less severe superstrains, at the same time reducing the size of the pool [ 44].

To determine the effects that increasing the division radius has on the ability of a cell with superior replicative fitness to invade, a single mutant cell with replication potential r B = 1.5 is introduced into a background of cells with replication potential r A = 1, see figure 4. All cells (mutant and wild type) have division radius ν A = ν B = ν.

Hence, the clinical efficacy of replication-competent adenovirus is superior to non-replicating adenovirus.

The protective efficacy of replication-competent viral vectors may theoretically be superior to that of replication-incompetent viral vectors, as they might elicit different or more comprehensive innate, cellular, and humoral immune responses.

Larger population sizes allow greater selection intensity and probability of identifying superior recombinants, whereas increased replication improves heritability, especially for highly complex traits prone to measurement error and random environmental deviations.

Using a HBV transgenic mouse model of chronic HBV infection, we recently reported high efficacy of transduction and superior silencing of HBV replication by HD Ads expressing previously designed artificial antiviral pri-miR and pre-miR mimics [ 11, 13].

These combinations were all conceived based on the prototypical polypharmacology hypothesis that targeting two different nodes of HCV replication may exhibit superior antiviral activity compared to single drugs and reduced resistance [11].