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In addition to the two background factors mentioned above, there is one special situation for oral cancer: superficially spread varieties, which we have called superficial carcinoma, have recently been increasing in number [ 3, 10– 10].
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Recent technological advances have allowed superficially spreading intramucosal carcinomas of the esophagus to be successfully resected by circumferential endoscopic submucosal dissection (cESD).
She had been treated in 2001 for a superficially spreading melanoma, Breslow depth 1.4 mm.
Yasuda K et al. defined a tumor measuring ≥ 5.0 cm as superficially spreading cancer of the stomach [ 22].
Subanalyses including superficially spreading and nodular melanomas only showed a significant correlation of cytoplasmic MSX2 positivity with both recurrence-free (P=0.015; Figure 6B) and overall survival (P=0.024; Figure 6D).
However, changes in tumour characteristics have occurred, since the proportion of superficially spreading malignant melanoma increased from 35% in 1960-64 to 51% in 1980-84 and the proportion of acral lentiginous melanoma decreased from 11%to2%2%.
Gr-LST are composed of superficially spreading aggregates of nodules forming flat, broad-based lesions with a granulonodular and uneven surface, whereas NGr-LST are lesions with a flat, smooth surface without granulonodular features [ 2].
Although LS exhibits regular cell proliferation and differentiation and a superficially spreading dormant growth [ 13], it is suggested that LS itself is not a marker of persistent tumour dormancy but has the potential to progress to an advanced stage with the prognosis as poor as that for LS−/TC+ UGCs.
Superficially, his viral spread into the more conventional corners of R&B and hip-hop isn't dissimilar to the one executed by T-Pain in the 2007-8 era.
On September 5, 1999, the lime by-product was spread superficially on the experimental subplot selected, just before the beginning of the autumnal rain season.
In carcinoma in situ (stage 0) tumours are usually small but may spread superficially and involve a large part of the oesophagus.
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