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The method, based on the preparation and superficial staining of slices 300 μm thick, enables "real" (i.e., unstained) trabecular termini to be separated from "artifactual" (i.e., stained) termini, providing a direct measure of cancellous connectivity in osteopenic bone.
The findings from the studies[36, 46, 52] after oral exposure suggested that nano-TiO2 could induce the damage to the liver and pathologic examination showed that in the liver tissue, the hydropic degeneration of the hepatocyte around the central vein was found, with hepatocyte disorder, superficial staining of cytoplasm osteoporosis.
The pyloric gland adenoma showed focal positive staining for MUC1, and negative staining for MUC2, as well as superficial staining for MUC5AC, and positive expression of MUC6 and VEGF.
MoAb 5.48 binds preferentially to the superficial cell layers of normal urothelium and well differentiated TCCs, but exhibits less binding in poorly differentiated tumours with loss of the preferential superficial staining.
Similar(56)
There was increased staining within superficial malignant cells in direct contact with the gastric lumen that did not appear artefactual.
Immunohistochemical results were scored blindly and semiquantitatively, using a scale of 0 3 for intensity, with patterns of staining in superficial vs. deep dermal cells also noted.
Other sections were scored for loss of safranin-O staining as a measure of cartilage proteoglycan depletion using a scale from 0 to 3, where 0 = no depletion; 1 = depletion of staining and thinning down of the lateral superficial layer; 2 = depletion of staining and thinning down of the central superficial layer; 3 = severe and mostly complete depletion of staining in the superficial layer [ 18].
Specifically, THBS1 was expressed throughout the CP at more lateral levels and in a thick, heavily stained, superficial part of the CP at the most ventral levels.
19A211 preferentially stained superficial tumours, and T43, T138 and EGFR preferentially stained invasive tumours.
In colonic adenoma pThr187-p27 positive cells were randomly located throughout the crypts and in contrast to that seen in normal mucosa, also superficial cells were stained.
Furthermore, the finding that resting light intensity can also show a signal increase with "bleaching" (Figures 2 and 3) suggests that the dye molecules staining meningeal and superficial tissue elements may have a physical microenvironment leading to fluorescent emission with lower efficiency.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com