Exact(4)
The optimal cutoff points are the values yielding maximum sums of sensitivity and specificity from the ROC curves.
For the cutoffs calculated for retinopathy, the sums of sensitivity and specificity were in the range of 1.5 1.6 in most studies, and thus demonstrated that cutoffs of HbA1c were much sharper in retinopathy than in other microvascular complications.
We estimated sex-specific cutoffs for the informative biomarkers that maximized the sums of sensitivity and specificity for predicting new-onset MetS by examining separate receiver-operating characteristics curves.
The sums of sensitivity and specificity calculated for these cutoffs in the Malay study are in the range of 1.1 1.2, which is again quite poor – remember that a figure of 1 for the sum of sensitivity and specificity corresponds to the minimum of information possible.
Similar(56)
The value of t γ was determined by identifying where the sum of sensitivity and specificity is maximal.
Optimal cutoff values were obtained with the greatest sum of sensitivity and specificity using the Youden index [18].
For most purposes, the algorithm that gives the highest overall diagnostic accuracy (sum of sensitivity and specificity) is preferable.
The optimal cutoff value of CRP was defined as the value associated with the highest sum of sensitivity and specificity −1 (Youden index).
Our study showed that at a cutoff scores of 5 in the GAD-7 and 1 in the GAD-2 had the highest sum of sensitivity and specificity.
From this, a cutoff for mortality based on NRBC was specified according to Youden's method (representing the highest sum of sensitivity and specificity) [17].
We chose a threshold value for selecting ES cells based on the sum of sensitivity and specificity values.
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