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After the evidence is collected and summarized, GRADE provides explicit criteria for rating the quality of evidence that include study design, risk of bias, imprecision, inconsistency, indirectness, and magnitude of effect.
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BRCA1-likeCGH tumors were more often ER-negative (36/42, 86%; Table S1 in Additional file 1) than BRCA2-likeCGH tumors (16/51, 31%; Table S2 in Additional file 1). Figure S1 in Additional file 2 summarizes grade, receptor and BRCA-likeCGH status per patient.
Toxicity data was reviewed and summarized by grade.
Safety was assessed with serial blood chemistry panels and symptom assessment, performed at baseline and study visits at weeks 1, 3, 7, 9, and 12. Adverse events were summarized by grade defined by Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 [ 30].
A scoring system called the 'gene-expression grade index' (GGI), which essentially summarizes the grade reporting genes by their average expression level, was introduced.
In our case evidence was summarized and graded by only two to three people.
#Diff – summarized tumor degree of differentiation from grade.
As shown in Table 1 (which summarizes the grading of inflammatory cell infiltration) and Table 2 (which summarizes peribronchiolar/perivascular fibrosis) in H&E-stained lung sections, both ApoE−/− and DKO mice had significantly greater immune cell infiltration after 3, 9, and 30 days of exposure to asbestos compared with exposure to clean air (p < 0.001).
Level of education summarized as primary school grade of 1 or higher versus no schooling or nursery was significantly related to One Card Learning Accuracy (coefficient = 0.35, standard error = 0.15, p = .02) and Errors in Maze Learning (coefficient = 0.38, standard error = 0.18, p = .03).03
Detailed or lengthy answers to participants' questions were summarized on a 7th grade reading level and sent to each participant in a follow-up letter from the medication coach.
Survivin, Survivin-∆Ex3, and Survivin-2B expression and tumor grade is summarized in Table 3.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com