To facilitate the summarization of the performance in each cognitive domain across different types of outcome parameters (e.g., accuracy, RT), each outcome parameter was normalized and fit to an IQ-like scale (mean: 100, SD: 15) in an age- and education-specific fashion.
In microarrays that use multiple short probes for each transcript, the probes are collectively referred to as a probeset, and the expression level reported for the gene is a summarization of the signal reported for each of the individual probes in the probeset [3].
Raw microarray data from CEL files were read with 'affy' package [26] and pre-processed by GC-RMA algorithm that performs the three steps: (i) adjustment of the gene expression signal against the background caused by optical noise and non-specific binding, (ii) robust multi-array normalization, and (iii) summarization of the probes belonging to each probe set.
Robust multichip averaging (RMA) algorithm was applied for background correction and probe summarization of perfect match values in each microarray chip.
Raw microarray data from CEL files were read with 'affy' package [ 22] and pre-processed by gcRMA algorithm (GC Robust Multiarray Average) that performs the three steps: (i) adjustment of the gene expression signal against the background caused by optical noise and non-specific binding, (ii) robust multi-array normalization [ 23], and (iii) summarization of the probes belonging to each probe set.
Raw microarray data obtained from CEL files were pre-processed by the gcRMA algorithm (GC Robust Multiarray Average) [ 22] that performs the three steps: (i) adjustment of the gene expression signal against the background caused by optical noise and non-specific binding, (ii) robust multi-array normalization [ 23], and (iii) summarization of the probes belonging to each probe set.
Comparisons are made between each current SMR and its originating design, obtaining a summarization of the development course and the innovation features of each SMR version.
Short probe platforms require an averaging or summarization of a set of probes for each gene.
Continual and automated extraction, analysis and summarization of EHR data could advance surveillance in each of these domains.
RM is useful to investigate unidimensionality of the construct (fundamental requisite of the summarization of the raw scores), the fit and the reliability of each item, and the differential item functioning.
