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The health index is a sum of risk factors representing an individual risk profile.
We used the sum of risk alleles from the dominant models, as the numbers of the rare homozygous genotype were too low to analyse as single genotypes.
In addition, subgroups of either a "low" or a "high" sum of risk alleles were defined, the cut-off point being determined by the median sum of risk alleles in the whole population, namely 17 risk alleles.
The sum of risk scores was related to a predicted probability for physical disability in the individual patient.
Again, a cut-off sum of risk alleles in biotransformation enzymes was assessed based on the median value, namely 5.
The Gmean OR, mean of sum of risk alleles and mean cumulative GRS values were compared between groups with Student t tests.
Similar(37)
Yet the sum total of risks — higher oil prices, a widening war — also provide Syria (and its patrons, Iran and Russia) a motive to negotiate.
The sum of risks due to noncarcinogenic adverse effects of trace elements was higher in groundwater than surface water.
This analysis allows us to test whether mortality risk is truly additive over time, and if so, to compare the sum of risks and to make inference on the difference between sums of risks.
Differences between the two age groups concerning these sums of risk alleles were initially examined using the Mann-Whitney U test.
The prevalence of these "low" and "high" sums of risk alleles for each biological pathway were compared between the two age-groups by Chi-Square analysis using a 2 × 2 cross table.
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