Sentence examples for sum of gene from inspiring English sources

We do not claim that the mesothelial cells of these two membranes have different profiles, as these cells were not microdissected and analysed separately, but the sum of gene expression from all the cells give a picture of the activities of the two membranes.

(ii) Sum of Gene EST must be less than 400.

In the validation cohort, prognostic index for each patient was defined as a sum of gene expression values multiplied by their corresponding coefficients derived from the Cox regression.

It has recently been suggested that a phenotype is not only the sum of gene effects but also the product of complex interactions among genes [ 24- 26].

The score for a GO term is then the sum of gene scores for its members, divided by the total number of binding sites for the miRNAs.

Thus, the observed gene expression level in a sample prepared from a total testis is a sum of gene expression levels from individual cell types.

Since a TSR is a weighted sum of genes, TSR scores can be calculated for each observed expression array (TSR profiling).

We used average linkage hierarchical clustering according to the Euclidean distance measure (square root of the sum of the squared differences in each dimension) by using the Cluster 3.0 software.[26] Since a TSR is a weighted sum of genes, a so-called TSR score can be calculated for each individual sample.

To compare overall methylation levels by tumor type, the number of methylated genes for each patient was calculated as the sum of genes with any degree of methylation and the average value for normal samples was compared to the average for each tumor type using an analysis of variance.

In microarray studies small sample sizes often present a major problem, such as overfitting, i.e. finding a discriminatory pattern by chance, which may occur when large numbers of genes are used to discriminate a small number of phenotypes.[7] Since a TSR is a weighted sum of genes, a TSR score can be calculated for each observed expression array.

Furthermore, to validate that the identified TSRs were not artifacts of gene selection, we applied the split-half method on each TSR.[21] As described above, a TSR is a weighted sum of genes and a so-called TSR score can be calculated for each sample.