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A 'sum-model' (3D QSAR – CoMFA) has been developed to design PPARα/γ/δ (peroxisome proliferator activated receptor) pan agonists by using the sum of activities (EC50) of compounds against individual subtypes as a dependent parameter.
The total MMP2 level was calculated as the sum of activities measured at 72 kDa (proenzyme) and 68 kDa (activated enzyme).
Marketing, the sum of activities involved in directing the flow of goods and services from producers to consumers.
From the contour map analyses the 'sum-model' was found to represent the three subtype specific models and also predicted the sum of activities of the training set molecules with reasonable accuracy.
The major Six1-expression domains during development were covered by the sum of activities of these enhancers, together with the previously identified enhancer for the pre-placodal region and foregut endoderm.
In our work, a use case is a sum of activities in a domain that allows answering product requirements.
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The broad principle of additionality – that charities add to the sum of activity rather than replace public services – is being dispatched with entirely.
The New York version, which started two years ago, is somewhat scrappier, although the sum of activity was impressive more than eight hundred events across five boroughs.
% soas : time evolution of the "Sum Of Activity" image_matrix = max 0, fliplr(xseq')'); % just to avoid infinitesimal negative value "-0.0000", which causes problem if imposed by '.^(1/3) etc'.
(This year's edition culminated with Pierre Boulez conducting Stravinsky beneath the pyramid at the Louvre). The New York version, which started two years ago, is somewhat scrappier, although the sum of activity was impressive more than eight hundred events across five boroughs.
The desired activity is set as the sum of activity bumps of height (f_{mathrm{pk}}) over each place field center.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com