Your English writing platform
Discover LudwigExact(2)
In sum, exposure by gavage or by swallowing a capsule may result in significant differences in toxicokinetics compared to an oral exposure that mimics the routes and timing of exposure to chemicals consumed in food or beverages.
In contrast there is no summation in Table 13 because it is inappropriate to sum exposure values from two or more different food groups for consumers only, because the consumers are different.
Similar(58)
For permethrin, we summed exposure variables for crop and animal applications because these were asked about separately.
We considered the use of a total (summed) exposure measure of all four PFC congeners; however, serum levels of PFOS were much higher than those of PFOA, PFHxS, and PFNA, suggesting that the combined analysis would disproportionately reflect PFOS levels.
In accordance with the REACH guidance, linear extrapolation was subsequently used to express the summed exposures in terms of additional cancer risk.
Biomonitoring has the advantage over environmental monitoring of providing integrating dosimeters summing exposures from all routes and may more accurately reflect the dose to the target tissue.
Aggregate daily exposure was calculated by summing exposures across all commodities: Summation of As exposures from every eating occasion for 1 day yielded the individual's daily tAs exposure.
This approach assumes that exposure to a mixture of substances, in which each component is at a subthreshold dose for toxicity, could result in an adverse health effect, when the summed exposures (weighted by their safe doses) exceed an HI of 1, as estimated in an iterative fashion.
The total exposure is, therefore, the sum of exposures during a given time and has thus the same dimension as exposure in general: (mass) × (time) / (volume) or (concentration) × (time), for example, with units μg d m –3.
The total exposure time was calculated by the sum of i) exposure time of implants followed for the whole observation period, ii) exposure time of the implants lost during the observation period, and iii) exposure time of the implants that did not complete the observation period.
After that the value has been compared to the oral NOAEL The influence of aggregate exposure on the MOE was assessed by comparing the MOE with the highest single exposure with the MOE for the exposure summed up for all scenarios for the same route of exposure [ 16].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com