Reads per million-normalized coverage was computed for the gene sets and regions indicated, and summary statistics were calculated at each base pair, for histograms or by summing total coverage across regions, as shown for boxplots.
Sequence coverage for regions 750 bp before and after start and end codons of regions of interest were extracted from the summed coverage profiles.
We used coverage, summed coverage over each branch of the bubble and the mean number of branching vertices of the sub-graph where the bubble resides (See Supplementary Table S1 for summaries of the datasets used for classification).
To determine the most likely state for any given expressed region, we weighted the Viterbi estimate of the state of each base in an expressed region by the summed coverage of that base.
We summed up the total coverage time of labor insurance as the duration of employment and further assumed that it could be used as a proxy of the amount of exposure to asbestos (subdivided into <1 year, 1 10 years, 11 20 years, and >20 years).
Figure 4 shows the relationship between the fraction of coverage attributable to the chimeric transcript, and the local total coverage, i.e. the sum of the chimeric and wild-type coverage.
Medicaid funding would change from total coverage for all medical bills of enrollees to a per capita lump sum for each enrollee.
(The sum of these optional sub-limits can exceed the size of the total policy, though the holder can only get up to the $10 million in total coverage).
Summed aligned coverage indicates the sum of the aligned region of contigs across the 13 mitochondrial genes.
In sum, media coverage represents neither the broad spectrum nor any specifications of scientific uncertainties.
The sum of coverage for each position in the window was computed, log10-scaled and plotted.
