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To invoke an analogy, Arg298 is like a latch on a suitcase, locking the active site barrel in cases in which the active site is appropriately packed.
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In the US, the Transportation Security Administration now lets you keep your suitcase locked, provided it's of an approved brand whose combo locks they can open.
The TSA, for their part, doesn't care, telling The Intercept that "The reported ability to create keys for TSA-approved suitcase locks from a digital image does not create a threat to aviation security.
We picked up our suitcases and locked the door, gave the key to the concierge, and boarded the RER to the airport.
The Bluesmart suitcase also has Bluetooth-enabled remote locking, so the suitcase automatically locks when you are out of range.
After the negotiations were complete, we carefully secured our treats, locking the suitcase with a little gold key that I kept around my neck for safe keeping.
11 There is no reason why the consignor of such a shipment would have any lesser expectation of privacy than the consignor of an ordinary locked suitcase.
The suitcase can be locked by a cellphone app, and it automatically locks if it is too far from the owner's cellphone.
A must when doing any traveling by air with curious hands running through your carry-on or locked suitcase.
The last time he exhibited it, at the National Sports Collectors Convention 20 years ago, he made the show's promoters hire a security guard who carried it around in a locked suitcase.
"We were never questioned, and our locked suitcases were never opened," he told a House panel.
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