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Suitable trial functions are proposed which satisfy the deformation compatibility and equilibrium equations.
Thereupon, we apply the following variational principle begin{aligned} delta langle Psi _mathrm{trial}|:{hat{H}}-E:|Psi _mathrm{trial}rangle _{t=0}=0, end{aligned} (2.16 where (|Psi _mathrm{trial}rangle ) is a suitable trial state with adjustable parameters or functions.
Two journals did not mention any suitable trial registry in their author instructions.
In the light of this, and after careful review of the evidence, our group felt that clinical equipoise exists, and that a suitable trial was therefore essential.
The relative isolation of Grande Comore, as well as the presence of population sub-division within the island, suggests that it may be the most suitable trial site for existing GMM technologies.
If the biomarker-positive subgroup is too small, it may be difficult to enroll a suitable trial, and if the biomarker-negative subgroup is too small, it may not be cost effective to screen when the error rate of the assay is considered.
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Three more potentially suitable trials were found but were excluded [15, 16, 17].
Authors, other experts in the field, and pharmaceutical companies were contacted for knowledge of suitable trials, published or unpublished.
Further details about identifying suitable trials were published previously [ 16].
Suitable trials published between 1990 and February 2011 were eligible for consideration.
Data from suitable trials were extracted by one author and checked by a second (JAF and DS).
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