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Initially the suitable mutation operators for both DEs used in DPD are investigated.
Therefore suitable mutation strategy for both DEs used in DPD is investigated over a set of 8 popular mutation strategies.
Moreover, the robustness of the mutation strategies of DE have been well studied and suitable mutation strategies for both DEs (for DPD) are investigated over a set of existing 8 popular mutation strategies which results 64 variants of DPD.
Firstly, in the mutation phase, an adaptive technique based on the deviation of objective function between the best individual and the whole population in the previous generation is proposed to select a suitable mutation operator.
If a suitable mutation density can not be reached with EMS, other chemical mutagens may need to be explored.
The relatively low amount of SNPs in BRCA1 and BRCA2 make HRM a suitable mutation scanning technique for these genes.
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Suitable mutations for changing such surfaces are discussed.
The regions and types suitable mutations for bridging salt-bridges to intensify enzyme stability are identified in this study.
Natural promiscuity, however, appears to be of limited scope in this context, because the latent (promiscuous) function is often related to the evolved one (sharing the active site and even the chemical mechanism) and its enhancement upon suitable mutations usually brings about a decrease in the native activity.
It appears that (a) the amyloidogenic properties of silkmoth chorion peptides are encoded into the tandemly repeating hexapeptides comprising the central domain of silkmoth chorion proteins, and, that (b) suitable mutations, properly and carefully designed, greatly affect the strong amyloidogenic properties inherent in certain aminoacid sequences and may inhibit amyloid formation.
In most cases studied, suitable mutations occur in the population prior to plating.
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