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These findings demonstrate that this fusion-deficient virus, which possesses uncleavable HA, is a suitable influenza vaccine candidate.
Both wild and domestic birds are suitable influenza virus hosts that mostly experience asymptomatic infections, despite high virus replication.
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This study assessed whether ambulance dispatch data are suitable for influenza surveillance.
12 The provision and use of antiviral agents will have challenges not faced by industrialised countries, due to the cost of providing an antiviral stockpile and subsequent distribution of antivirals in countries which have health systems already stretched to capacity. 15 The importance of suitable pandemic influenza preparedness plans for low-income countries is recognised by the WHO.
B cells were chosen as a model as they represent a suitable target for influenza virus in vitro [29].
Standard fluorometric endpoint assays used to monitor NA activity was recently shown to be suitable to quantify influenza virus in a high-throughput screening test [26].
Each year, WHO recommends the most suitable composition of influenza vaccine strains for the Northern and Southern Hemispheres, based on phylogenetic analyses of HA and antigenic characteristics of circulating viruses.
They are specifically suitable for modeling influenza pandemic since they allow the modeling of the contacts of the specific places where groups of individuals spend much of their time together, i.e. households, schools and workplaces.
The results from fluorescence microscopy and flow cytometry indicated that the combination of antibodies used is suitable not only human influenza A strains, but also for the detection of equine and porcine influenza A virus infection in cultured adherent MDCK cells.
These highly conserved viral genes may require combinatorial vaccination with HA to be suitable candidates for universal influenza vaccines.
Ferrets are broadly accepted as suitable animal models for influenza virus infection and transmission in humans [10], [23].
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