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FEX is rapidly absorbed with a long duration of action, making it suitable for once daily administration.
Both agents have good oral bioavailability and are suitable for once daily administration.
When boosted by ritonavir, elvitegravir's systemic exposure is increased by 20-fold, thus allowing persistent plasma levels suitable for once daily dosing.
Efforts targeted a half-life suitable for once- (qd) or twice-daily (bid) dosing, without large differences in peak and trough concentrations.
Liraglutide is an investigational human acylated GLP-1R agonist approved in Europe that binds noncovalently to albumin and exhibits a more prolonged duration of action suitable for once daily administration.
A longer-acting microsphere preparation of exenatide suitable for once weekly administration, exenatide (once weekly), has also been studied in controlled clinical trials and appears to be somewhat more effective compared with exenatide twice daily (5).
Similar(54)
The pharmacokinetic properties of an optimized analog (9) were characterized in several preclinical species, demonstrating pharmacokinetic characteristics suitable for once-a-day dosing in humans.
Overall, the TBS-NCT system appears suitable for once-daily application as an aid in smoking cessation treatments.
43 This protracted action profile makes liraglutide suitable for once-daily administration.
The long elimination half-life of tadalafil makes it suitable for once-daily dosing.
Its long half-life makes it suitable for once-daily oral administration.
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