Sentence examples for suitable for mutations from inspiring English sources
They should both be discarded from the alanine scanning protocol: alanine is already present in the structure while proline is not suitable for mutations because of the major protein backbone rearrangements that should be performed to properly mutate it.
It also permits standardization of DNA melting experiments and the introduction of instruments of a "lower level" into the range of those suitable for mutation scanning.
Only samples positive for both PCR products were considered to contain successfully amplified genomic material suitable for mutation analysis.
Two-Temperature LATE-PCR using a single mismatch-tolerant probe may also be suitable for mutation scanning.
This finding stresses the need for use of a combination of criteria in the selection of patients suitable for mutation screening.
In addition, with the availability of genetic testing for BRCA1 and BRCA2 mutations within high-risk families, the morphological and molecular phenotype may help to identify patients who are suitable for mutation testing of specific genes.
As PCR SSCP method is very suitable for detecting mutations within a relatively limited region such as EGFR gene mutations and has been already used to detect p53 gene mutations commercially, the method can be more easily applied to detect EGFR mutations in clinical setting than direct sequence.
We used the results from this computational modeling to design a bulk segregant mapping experiment suitable for identifying mutations in yeast causing small changes in expression of a yellow fluorescent protein (YFP) reporter controlled by the Saccharomyces cerevisiae TDH3 promoter.
Consistent with this, we found that incorporating a dI into the primer at the location of the polymorphism was a good strategy for eliminating the detection of the polymorphism while giving clean HRM profiles suitable for both mutation detection and downstream sequencing of mutations.
A total of 60 tumor samples were suitable for EGFR mutation analysis.
A recent methods comparison study suggested that a variety of techniques might be suitable for KRAS mutation testing.
