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This profile was very close to that obtained recently with 5-HT, which suggests an implication of 5-HT in the spinal antinociceptive effect of acetaminophen.
Thus, our study suggests an implication of miRNAs in microbiota-mediated host gene regulation.
The early and sustained activation for peripherally presented faces suggests an implication of somatosensory areas not only in internal somatic representation of the emotion [77] but also in fast detection and reaction to danger.
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Our data suggest an implication of RAI in septic cardiomyopathy.
Overall we found a decrease of PGRPs expression when symbionts amount decreases, suggesting an implication of PGRPs in the regulation of symbionts in B. azoricus gills.
These results suggested an implication of the p300 coactivator in preventing VRK1 downregulation by p53.
Recent studies in the ferret suggest an implication of A1 because after alteration of binaural cues, ferrets can recalibrate a sound source location by using visual cues [56], a mechanism that involves the primary auditory cortex [53].
Interestingly, both PARVA and PARVB are down-regulated during the later phase of the CAM, when the endothelium becomes quiescent, suggesting an implication of these two genes earlier in CAM angiogenesis.
Analysis of marker gene expression using these HIFs indicated a negative correlation between the induced amount of transcripts of SA-dependent genes PR1, ICS and PR5, and the in planta bacterial growth in the HIF segregating at PRP-Ps2 locus, suggesting an implication of PRP-Ps2 in the activation of SA dependent responses.
GRIA3, which was also confirmed to be differentially expressed by SemiQ RT-PCR (Table 5), is of particular interest in suicide as it was significantly down-regulated in the prefrontal cortex in both suicide groups (BA46, Figure 4), with and without major depression, suggesting an implication in suicide irrespective of the presence of major depression.
Thus, the differences observed between the HIFs for in planta bacterial growth at the PRP-Ps2 locus can be correlated with those observed for expression of SA-dependent genes, suggesting an implication of PRP-Ps2 in the activation of SA dependent responses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com