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The paper recognised that aim to keep the tax take at 23.9% would have been harmful during the contraction, but suggests a modest increase in tax could now help achieve a budget surplus earlier than the 2020-21 projection.
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Data from the National Databank of Rheumatic Diseases suggested a modest increase in lymphoma [ 59] and an increased risk for skin cancer in patients treated with TNF inhibitors [ 60].
Previous studies suggest a modest increase in risk of breast cancer among women with type 2 diabetes and gestational diabetes [ 5].
Inconsistent data have been reported for prostate cancer (Wolk et al, 2001; Larsson and Wolk, 2006) but most studies have suggested a modest increase in risk of advanced prostate cancer with increasing body mass.
This was supported by constrained geometric simulations that suggested a modest increase in mobility when these salt bridges were removed, albeit in a model where our understanding of structure in the TM3-TM4 domais is unavoidably compromised.
For example, several studies suggested a modest increase in the risk of colorectal cancer associated with smoking [ 8- 11], but other studies failed to find such a positive association [ 12- 14].
Several large prospective randomised clinical trials have suggested a modest increase in relapse-free survival (RFS) with chemotherapeutic treatment intensification in patients with 10 or more positive axillary nodes, while others have not (Roche et al, 2003; Rodenhuis et al, 2003; Tallman et al, 2003; Zander et al, 2004).
Compared with those in the general population, the SIR estimates for patients with RA suggest a modest increased risk in overall malignancy, as previously observed.
Figure 4 suggests that a modest increase in contraceptive prevalence to 15% could reduce unmet need for family planning by 8% (from 54.8% to 46.6%).
He suggests that a modest increase in the allocation to prevention would enable significant advances to be made across a wide range of public health activity and research areas.
Importantly, ω3 PUFAs have shown beneficial effects on bone health in animal studies [ 164, 165] but current research suggests only a modest increase in bone turnover in humans [ 166].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com