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Tcf21 null mutants have several testis phenotypes [14] suggesting multiple roles for TCF21 in testis organogenesis.
Several reports have identified Grp78/BiP localization on the plasma membrane or cytosol, suggesting multiple roles beyond ER stability and UPR modulation.
Similarly, RacB was predominantly expressed at the secondary wall synthesis stage in TM-1, and preferentially expressed at the initiation of fiber development and secondary wall synthesis in Hai7124 (Additional file 6: Supplemental Figure S3D), suggesting multiple roles for RacB.
Hrp36, an hnRNP A1-like protein, and the Y-box p50 protein (Soop et al. 2003) both bind to BR1 and BR2 pre-mRNPs cotranscriptionally and remain associated with the BR mRNPs in polysomes, suggesting multiple roles for these proteins.
There is, however, good evidence to show that the intermediate enzymatic activity of PI5P4Kβ does have physiological relevance [ 12, 24], suggesting multiple roles for the PI5P4Ks that are possibly tissue- and cell-type-specific.
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These findings suggest multiple roles for the OsWRKY125 gene, including recognition of pathogens, signal transduction, and stimulation of defense gene functions.
Accumulating evidence has suggested multiple roles for EPCs in endothelial physiology, such as neovascularization, endothelial repair and restoration of endothelial function [6].
The full positive charge on the Mg2+ and the architecture of the active site suggest multiple roles for Mg2+ in DNA cleavage.
These results suggest multiple roles for TXNL6 in the eye lens including epithelial metabolism and maintenance of fiber cells.
Our results suggest multiple roles of GS in maintaining barrier structure and function of skin supported by novel specific regulatory features.
While the above results suggest that unc-51 regulates intracellular trafficking of various vesicles and molecular cargos in developing MB neurons, previous studies have suggested multiple roles for unc-51 in diverse cellular and neuronal processes [12], [13], [15], [17], [23], [37], [38], [40], [41], [42], [43].
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