Hence, given the abundance of sequence variation evident here, functional differentiation of tandem duplicates may be commonplace, suggesting a subtle functionality within tandem arrays not yet appreciated in T. brucei.
With the exception of predicted phosphorylation sites of RID beta, previously described functional sites and motifs are conserved in HAdV-A31 and HAdV-A12, suggesting a comparable functionality.
The same study grouped the other two T6SSs that were observed here, in a widely distributed T6SS class present in both animal and plant pathogens, suggesting a broader functionality.
These members are both highly interconnected and relatively separated from all other clusters (i.e. few connections with genes outside the cluster), suggesting a shared functionality that has relatively low dependency on all other genes.
On the other hand, both lineages have undergone gene duplications and, for example, genes related with olfaction, immunity and reproduction expanded in the rodent lineage, suggesting an extended functionality [ 7].
The cells that did not express BRCA1 had reduced RAD51 foci formation upon DNA damage, suggesting a deficient HR functionality (Fig. 3b,c).
These findings suggest a novel functionality to stainless-steel surface modification.
Our results suggest a dual functionality for the members of the hPAF complex.
Our densitometric data suggest a different functionality of the two anatomic MC populations examined, since degranulation was found to be more prominent in perifollicular than subepidermal MCs.
The functional significance of LR1 is unknown, however the high conservation observed within isoforms suggests a likely functionality related to PDE4 gene isoform-specific sequence identity.
