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Also residues in the peptide are rather disordered; these observations bring into question the suggested triggering role of the peptide in the formation of a 2∶2 complex [14].
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In young healthy animals evidence suggests triggering the sterile inflammatory response promotes survival, facilitating innate immune responses to potential infection after injury.
While the former lends support to the hypothesis that slow slip triggers earthquakes on locked asperities within the slip zone, the latter suggests triggering by increased static stress.
The rapid onset of these responses suggests triggering by sensory irritation originating in the nose or lung.
Activation of caspase-9 suggests triggering of the mitochondrial pathway of cell death, characterized by the lost of mitochondrial membrane integrity, mitochondrial cytochrome c release to the cytosol and activation of caspases-9 and -3.
Some of the suggested trigger warnings – on Ovid's Metamorphoses, for example – are absurdly over the top, and we do need to watch out for a creeping chilling effect, but in moderation, where reasonably called for, why not?
Second, there is concern related to the suggested trigger for VSG switching: expression of a new VSG.
A group of consultants, junior doctors and nurses from the ICU and the ward each read the patient files with focus on pattern recognition and suggested trigger points to focus on.
Previous studies suggested that triggering receptor expressed on myeloid cells-1 is upregulated in the presence of infection.
These findings suggested the triggering of unique signaling pathways in metastasis for homing of breast-cancer cells to congenial environment of specific organs.
For pre-menopausal node-positive patients, the abrupt increase of the first narrow peak of the recurrence risk suggests a triggering event that synchronises early risk.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com