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Similarly, phosphorylation of dynamin has been suggested to regulate the rate of synaptic vesicle endocytosis (SVE) [40].
Initially, the functional interaction between BRCA1 and Sp1 was suggested to regulate the IGF-I-R, a receptor overexpressed in most breast cancers that serves as an antiapoptotic factor [69], [70].
C-fos, as a protooncogene, has been shown to act as an inducible transcriptional factor and suggested to regulate the expression of the downstream response genes [6], [19], [20].
Furthermore, Hand1 has been suggested to regulate the balance between cardiomyocyte differentiation and proliferation.
Akt activation was suggested to regulate the nuclear translocation of transcription factor YB-1, affecting the expression of MDR1.
For example, multiple proteins were detected that have been suggested to regulate the pluirpotent state in mouse ESCs or hESCs.
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Interestingly, NIX was previously suggested to regulate MPTP in the context of non-apoptotic cell death [12].
Interestingly, the lncRNA from the SNPRN-UBE3A region has been suggested to regulate another imprinted locus, the DLK1-DIO3 region, which is the only other known imprinted cluster of ncRNA that produces lncRNA, miRNA, and snoRNA.
In a series of unrelated studies, Wnt signalling, as the central signalling cascade regulated by fezf2, has been suggested to regulate neuronal differentiation and the assembly of neural connectivity and synapse formation and function (Munji et al., 2011; Oliva et al., 2013).
In the study by Zhang et al., endoglin was suggested to regulate primitive hematopoiesis by modulating the activity of the Smad1/5 signaling pathway at early stages of development.
PECAM-1, a member of the immunoglobulin superfamily, localizes close to interendothelial clefts and has been suggested to regulate PMN migration in the pulmonary vasculature.
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